Usiko’s work focuses on youth aged 12 up to 18 years. The focus includes "children of impoverished farm workers and adolescents from townships and remote rural settlements as well as young offenders referred by the court system". A central feature of Usiko’s intervention is its wilderness therapy, which enables the participants to "explore personal issues and develop skills in leadership as well as raise awareness of, and connection to nature". The wilderness therapy therapy has gained worldwide recognition as a best-practice model and is accredited through the Department of Social Development.

The Trust’s funding is used for the Schools-based prevention and Sustainable livelihoods programmes. These programmes aim to aid the transition into the working world through vocational skills, internships and help with accessing bursaries and further education".